What about pesticide exposures in older adults?
Some groups of people, such as older adults, people with health
conditions, those who are pregnant, or infants and children, may be
more sensitive to pesticides. The size of the elderly population is
increasing. Recent studies show that by the year 2030 one out of every
five Americans will be age 65 or
older.1 This
fact sheet provides
a summary of factors that could increase the pesticide risk for older
adults.
Can pesticides enter the body more easily as people age?
In order for a pesticide to affect you, it must be absorbed into
your body by swallowing it, breathing it, or getting it on your
skin. As we grow older, the chances of absorbing pesticides into the
body may increase for several reasons.
The outer layers of our skin become thinner as we age. Because of
this, pesticides that are absorbed through the skin of young, healthy
adults may enter more quickly through the skin of older
adults.2 This
may cause an older
person to absorb more of a pesticide compared to a younger person,
even if the amount of pesticide that contacts the skin is the
same.
The thinner skin of older adults is also more easily damaged upon
contact with a pesticide. This damaged skin, however, is slower to
become red or irritated. It may take longer for older adults to
realize that they need to wash harmful chemicals from their skin
simply because it takes longer for the skin to react to the
pesticide.3
Because older adults
may be exposed for longer periods, they may absorb more pesticide than
a younger person would.
As we age, our nervous system changes in ways that can affect how
easily we notice changes to our surroundings through our sense of
smell, touch, or taste.3 Because
of this, aging may also affect how quickly we respond to odors and
skin sensations. Slower response times may make it difficult for
older adults to determine when they are being exposed to a pesticide.
Older adults may absorb more pesticides into their bodies simply
because they may be exposed for longer periods.
Why is it harder for older adults to remove pesticides from their bodies?
The ability of the heart to move blood around the body declines as
we age.4 This
reduces blood flow
to the liver and kidneys, which also decrease in size as we grow
older. Reduced blood flow and decreases in liver and kidney size can
work together to slow the break down and removal of pesticides from
the body.2,3,5
Does aging effect how the body stores pesticides?
People tend to gain body fat and lose lean muscle as they age. The
body stores many pesticides in fat before they are removed from the
body by the liver or kidneys. Pesticides that are stored in fat can
build up in larger quantities in the bodies of older adults. Because
of this, older adults may experience health problems from pesticide
exposures that may not cause problems for younger
adults.2,5
The body also stores pesticides in the blood and other body
fluids. Such pesticides may stay in the bodies of older adults longer
if aging kidneys are not as effective in removing
them.3
What effects could result from pesticide exposures in
the elderly?
Older adults may be more likely to have health problems after a
pesticide exposure and may need more time to heal for the following
reasons.
- The liver and kidneys become less able to remove pesticides from
the body as we age. Pesticides may speed up aging of the liver or
kidneys if these organs are injured during an
exposure.2,5
Older adults
may
become even less able to remove pesticides from the body after the
liver or kidneys are impacted.
- The longer a pesticide stays in the body, the more likely it is to
build up to levels that may cause
injury.2 Older
adults may
have
health problems after a pesticide exposure simply because their bodies
can no longer remove pesticides quickly.
- Chemicals such as prescription drugs or pesticides can react with
each other once they are inside the body. These chemical reactions may
cause unexpected health effects in older adults for two
reasons. First, older adults may take more prescription medications
than younger people. Second, chemicals stay in the bodies of older
adults longer, so they have more time to react. Both of these reasons
increase the chance that a drug will interact with a pesticide that
enters the body.2
What other factors can increase pesticide risk for older adults?
Older adults may take more prescription drugs than younger
people.2 Most
pesticides are
broken down and removed from the body by the liver and kidneys. These
organs also remove prescription drugs from the body. The liver and
kidneys may become less able to remove pesticides from the body if
someone is taking several types of prescription
drugs.5 Older
adults are also
more likely to suffer from diseases of the liver, kidneys or other
organs that help remove pesticides from the
body.5
Disease can reduce the
ability of older adults to remove pesticides from the body and may
increase pesticide risk.
What precautions can help elderly people minimize the
chance
of
having a problem
Older adults can reduce their pesticide risk
by minimizing their
exposure to
pesticides, choosing pest control measures that do not involve
pesticides or by selecting less toxic pesticide products. Consider
using an Integrated Pest
Management
(IPM)
approach to pest control. If you want to know more about IPM or about
the toxicity of a pesticide product, call NPIC at
800-858-7378.
Anytime you use a pesticide, be sure to read and follow the label
instructions. The label will include important information for
protecting yourself, such as protective clothing that should be worn
when applying the product. Wash your hands, face, and clothing after
you finish handling a pesticide.
If pesticides are being used near you, ask for details about the
activity, such as where it is happening, how much area is being
treated, and what pesticide is being used. Ask the person who is using
the pesticide what precautions you should take, such as leaving the
area for a period of time.
If you have been exposed to a pesticide, take note of the situation
in which it happened. The length and amount of exposure are important
details for understanding your risk. Read the first aid statement on
the product label,
and follow the instructions.
NPIC aims to use the best scientific resources available at the time fact sheets are written. NPIC does not have the resources to keep all of its fact sheets entirely up to date. All NPIC documents indicate when the material was last updated. For more information on how NPIC selects scientific resources, visit our web page Writing NPIC Fact Sheets.
For more detailed information please visit the list of referenced resources below, call NPIC at 800-858-7378 (8:00am - 12:00pm PST), or email us at npic@oregonstate.edu.
Date Reviewed: December 2011
- The State of Aging and Health in America 2007; U.S. Department of Health and Human
Servicecs,
Centers
for Disease
Control and Prevention and The Merck Company Foundation: Whitehouse Station, NJ, 2007.
- Risher, J. F.; Todd, D. G.; Meyer, D.; Zunker, C. L. The elderly as a sensitive population in
environmental
exposures: Making
the case. Rev. Environ. Contam. Toxicol. 2010, 207, 95-157.
- Masoro, E. J.; Schwartz, J. B. Exploration of aging and toxic response issues; U.S.
Environmental
Protection Agency, Risk
Assessment Forum, EPA 630-R-01-003: Washington, DC, 2001.
- Goldspink, D. F.; Burniston, J. G.; Tan, L.-B. Cardiomyocyte death and the ageing and failing
heart.
Exp.
Physiol. 2003, 88 (3),
447-458.
- Ginsberg, G.; Hattis, D.; Russ, A.; Sonawane, B. Pharmacokinetic and pharmacodynamic factors
that
can
affect
sensitivity
to neurotoxic sequelae in elderly individuals. Environ. Health Perspect. 2005, 113 (9),
1243-1249.
NPIC fact sheets are designed to answer questions
that
are
commonly
asked by the public about pesticides that are regulated by the
U.S. Environmental Protection Agency (US EPA). This document is
intended to be educational in nature and helpful to consumers for
making decisions about pesticide use.